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Pharmaceuticals / services

Pharmaceutical

Voriconazole

Release time：2021-12-12

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INDICATIONS AND USAGE
Voriconazole tablets are an azole antifungal indicated for the treatment of adults and pediatric patients aged 12 to 14 years weighing greater than or equal to 50 kg and those aged 15 years and older regardless of body weight with:
?Invasive aspergillosis
?Candidemia in non-neutropenics and other deep tissue Candida infections
?Esophageal candidiasis
?Serious fungal infections caused by Scedosporium apiospermum and Fusarium species including Fusarium solani, in patients intolerant of, or refractory to, other therapy
DOSAGE AND ADMINISTRATION
Dosage in Adults

InfectionLoading doseMaintenance Dose

Intravenous
infusion		Intravenous
infusion		Oral
Invasive Aspergillosis6 mg/kg every
12 hours for
the first
24 hours		4 mg/kg
every
12 hours		200 mg
every 12 hours
Candidemia in nonneutropenics
and other deep
tissue Candida infections		3 to 4 mg/kg every 12 hours200 mg
every 12 hours
Scedosporiosis and
Fusariosis		4 mg/kg every 12 hours200 mg every 12 hours

 
Esophageal CandidiasisNot EvaluatedNot Evaluated200 mg every 12 hours

?
Adult patients weighing less than 40 kg: oral maintenance dose 100 mg or 150 mg every 12 hours.
?
Hepatic Impairment: Use half the maintenance dose in adult patients with mild to moderate hepatic impairment.


Reprint statement: reprint please indicate "source: Wista pharma".

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